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Sergio Ruiz-Carmona
I am currently a Research Officer and Bioinformatician at the Baker Institute, under the supervision of professor Mike Inouye. My research interests are broad and involve mainly the relationship between genetic variants and their effect on protein structures.
I carried out my MSc and PhD in Barcelona in the Barril Lab, where I worked with different structure-based drug design methods with the aim to improve drug design for non-standard targets.
Selected Education
PhD in Biomedicine
Universitat de Barcelona
Barcelona, ES
2017 - 2012
- Virtual Screening for novel MoA: Apps. and method developments
- Development and application of structure-based drug discovery methods
- Awards: Extraordinary prize for PhD Thesis and Ramon Margalef award for best publication
Selected Positions
Research Officer and Bioinformatician
Inouye Lab
Baker Heart and Diabetes Institute
Melbourne, AU
Today - 2019
- I am working in a project that overlaps Structural Biology and Genomics, in collaboration with David Ascher’s Lab. Mainly, I am trying to understand how rare missense variants alter protein structures and can induce different diseases
Associate Professor
Faculty of Pharmacy, Universitat de Barcelona
Barcelona, ES
2019 - 2015
- Classes in Pharmacy, Food Science and Nutrition degrees (total 400h)
Predoctoral Researcher
Barril Lab, Universitat de Barcelona
Barcelona, ES
2016 - 2011
- Master’s and PhD research projects in the Xavier Barril Lab
Main Scientific Output
Oxygen Pathway Limitations in Patients with Chronic Thromboembolic Pulmonary Hypertension
Circulation
Read it here
N/A
2021
- Erin J Howden *, Sergio Ruiz-Carmona *, […] Andre La Gerche, Marion Delcroix and Guido Claessen
Var2Prot: A new tool to unravel the 3D structural effect of genetic variants
Lorne Proteins 2020
Oral Communication
Lorne, AUS
2020
Dynamic undocking and the quasi-bound state as tools for drug discovery
Nature Chemistry
Read it here
N/A
2017
- Sergio Ruiz-Carmona, P Schmidtke, […] Rod Hubbard and Xavier Barril
- Highlighted in its issue cover
rDock: a fast, versatile and open source program for docking ligands to proteins and nucleic acids
PLoS Computational Biology
Read it here
N/A
2014
- Sergio Ruiz-Carmona, Daniel Alvarez-Garcia, […] Xavier Barril, Rod Hubbard and S David Morley